The molecular basis of pH sensing by the human fungal pathogen Candida albicans TOK potassium channel

Summary: Two-pore domain, outwardly rectifying potassium (TOK) channels are exclusively expressed in fungi. Human fungal pathogen TOK channels are potential antifungal targets, but TOK channel modulation in general is poorly understood. Here, we discovered that Candida albicans TOK (CaTOK) is regula...

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Bibliographic Details

Published in:	iScience
Main Authors:	Rían W. Manville, Claire L. Illeck, Anthony Lewis, Zoe A. McCrossan, Steven A.N. Goldstein, Geoffrey W. Abbott
Format:	Article
Language:	English
Published:	Elsevier 2024-12-01
Subjects:	Natural sciences Biological sciences Microbiology Microbial physiology
Online Access:	http://www.sciencedirect.com/science/article/pii/S2589004224026786