Frequency and clinical relevance of DNA microsatellite alterations of the CDKN2A/B, ATM and p53 gene loci: a comparison between pediatric precursor T-cell lymphoblastic lymphoma and T-cell lymphoblastic leukemia

Although deletions of cell cycle regulatory gene loci have long been reported in various malignancies, little is known regarding their relevance in pediatric T-cell lymphoblastic lymphoma (T-LBL) and T-cell lymphoblastic leukemia (TALL). The current study focused on loss of heterozygosity (LOH) anal...

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Bibliographic Details
Published in:Haematologica
Main Authors: David Krieger, Anja Moericke, Ilske Oschlies, Martin Zimmermann, Martin Schrappe, Alfred Reiter, Birgit Burkhardt
Format: Article
Language:English
Published: Ferrata Storti Foundation 2010-01-01
Online Access:https://haematologica.org/article/view/5464