ALS-like pathology diminishes swelling of spinal astrocytes in the SOD1 animal model

Astrocytes are crucial for the functioning of the nervous system as they maintain the ion homeostasis via volume regulation. Pathological states, such as amyotrophic lateral sclerosis (ALS), affect astrocytes and might even cause a loss of such functions. In this study, we examined astrocytic swelli...

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Bibliographic Details

Published in:	Frontiers in Cellular Neuroscience
Main Authors:	Tereza Filipi, Jana Tureckova, Ondrej Vanatko, Martina Chmelova, Monika Kubiskova, Natalia Sirotova, Stanislava Matejkova, Lydia Vargova, Miroslava Anderova
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-10-01
Subjects:	amyotrophic lateral sclerosis SOD1 astrocytes volume regulation extracellular space potassium uptake
Online Access:	https://www.frontiersin.org/articles/10.3389/fncel.2024.1472374/full