Hyaluronic acid promotes biomineralization of osteoblast-like cells – observations on two different barrier membranes

Abstract Background Guided bone regeneration (GBR) relies on biocompatible membranes to support osteogenesis. 1,4-butanediol diglycidyl ether (BDDE)-crosslinked hyaluronic acid (xHyA) has shown promise in enhancing bone regeneration, yet its mechanisms remain unclear. Objective This study evaluates...

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Bibliographic Details

Published in:	International Journal of Implant Dentistry
Main Authors:	Daniel Diehl, Vincent Kabst, Tim Bürgel, Thomas Dittmar, Hagen S. Bachmann, Anton Pembaur, Anton Friedmann
Format:	Article
Language:	English
Published:	SpringerOpen 2025-09-01
Subjects:	BDDE-crosslinked hyaluronic acid Guided bone regeneration Collagen membranes SaOS-2 Osteogenesis Alkaline phosphatase
Online Access:	https://doi.org/10.1186/s40729-025-00646-2