A high-throughput cigarette smoke-treated bronchosphere model for disease-relevant phenotypic compound screening.

Cigarette smoking (CS) is the leading cause of COPD, and identifying the pathways that are driving pathogenesis in the airway due to CS exposure can aid in the discovery of novel therapies for COPD. An additional barrier to the identification of key pathways that are involved in the CS-induced patho...

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Bibliographic Details

Published in:	PLoS ONE
Main Authors:	Pranjali Beri, Young Jae Woo, Katie Schierenbeck, Kaisheng Chen, S Whitney Barnes, Olivia Ross, Douglas Krutil, Doug Quackenbush, Bin Fang, John Walker, William Barnes, Erin Quan Toyama
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2023-01-01
Online Access:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0287809&type=printable