Mechanism of spindle stability and poleward flux regulating spindle length during the metaphase

Summary: During metaphase, the spindle stabilizes chromosomes and maintains its size despite continuous microtubule poleward flux. To investigate the mechanism of the spindle stability and how the poleward flux regulates the spindle size, we establish a minimal spindle model that incorporates kineto...

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Bibliographic Details

Published in:	iScience
Main Authors:	Yao Wang, Yu-Ru Liu, Peng-Ye Wang, Hui Li, Ping Xie
Format:	Article
Language:	English
Published:	Elsevier 2025-10-01
Subjects:	Cell biology Organizational aspects of cell biology Bioinformatics
Online Access:	http://www.sciencedirect.com/science/article/pii/S2589004225017675