Relationship of mTORC1 and ferroptosis in tumors

Abstract Ferroptosis is a novel form of programmed death, dependent on iron ions and oxidative stress, with a predominant intracellular form of lipid peroxidation. In recent years, ferroptosis has gained more and more interest of people in the treatment mechanism of targeted tumors. mTOR, always ove...

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Bibliographic Details

Published in:	Discover Oncology
Main Authors:	Huilin Liao, Yueqing Wang, Lili Zou, Yanmei Fan, Xinyue Wang, Xiancong Tu, Qiaobai Zhu, Jun Wang, Xiaowen Liu, Chuanjiang Dong
Format:	Article
Language:	English
Published:	Springer 2024-04-01
Subjects:	Ferroptosis mTOR AMPK Autophagy GPX4 Tumors
Online Access:	https://doi.org/10.1007/s12672-024-00954-w