Generation of a TAB2 knockout hESC line (WAe009-A-Z) derived from H9 using CRISPR/Cas9

TGF-β-activated kinase 1 binding protein 2 (TAB2) is an intermediate protein that connects TNFR1 and other receptor signals to the TGF-β-activated kinase 1 (TAK1) signaling complex. TAB2 has been proved clinically relevant to congenital heart defects (CHD) and cardiomyopathy. In this study, we creat...

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Bibliographic Details

Published in:	Stem Cell Research
Main Authors:	Wenrui Sun, Xiaowei Li, Jianzeng Dong, Yangfan Zhou
Format:	Article
Language:	English
Published:	Elsevier 2024-02-01
Subjects:	TAB2 CRISPR/Cas9 Gene knockout
Online Access:	http://www.sciencedirect.com/science/article/pii/S1873506123002702