The TRPM2 ion channel regulates metabolic and thermogenic adaptations in adipose tissue of cold-exposed mice

IntroductionDuring thermogenesis, adipose tissue (AT) becomes more active and enhances oxidative metabolism. The promotion of this process in white AT (WAT) is called “browning” and, together with the brown AT (BAT) activation, is considered as a promising approach to counteract obesity and metaboli...

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Bibliographic Details

Published in:	Frontiers in Endocrinology
Main Authors:	Andrea Benzi, Markus Heine, Sonia Spinelli, Annalisa Salis, Anna Worthmann, Björn Diercks, Cecilia Astigiano, Raúl Pérez Mato, Adela Memushaj, Laura Sturla, Valerio Vellone, Gianluca Damonte, Michelle Y. Jaeckstein, Friedrich Koch-Nolte, Hans-Willi Mittrücker, Andreas H. Guse, Antonio De Flora, Joerg Heeren, Santina Bruzzone
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-02-01
Subjects:	TRPM2 ADPr white adipose tissue brown adipose tissue thermogenesis cold exposure
Online Access:	https://www.frontiersin.org/articles/10.3389/fendo.2023.1251351/full