The clinical and genetic spectrum of twenty-six individuals with hearing loss affected by MYO15A variants

Abstract Myosin XVA (MYO15A) is a member of the myosin superfamily that, as a motor protein, plays an essential role in actin polymerization at the tip of the stereocilia in hair cells. Variants in MYO15A are known to be the third most common reason for autosomal recessive non-syndromic hearing loss...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Saeid Morovvati, Mina Mohammadi Sarband, Samaneh Doostmohammadi, Sima Rayat, Hessamaldin Emamdjomeh, Mohammad Farhadi, Alimohamad Asghari, Masoud Garshasbi, Masoumeh Falah
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-04-01
Subjects:	Hearing loss DFNB3 MYO15A Domain Whole-exome sequencing Hair cell
Online Access:	https://doi.org/10.1038/s41598-025-99417-7