Interaction between tumor cell TNFR2 and monocyte membrane-bound TNF-α triggers tumorigenic inflammation in neuroblastoma

Background Tumor progression and resistance to therapy in children with neuroblastoma (NB), a common childhood cancer, are often associated with infiltration of monocytes and macrophages that produce inflammatory cytokines. However, the mechanism by which tumor-supportive inflammation is initiated a...

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Bibliographic Details
Published in:Journal for ImmunoTherapy of Cancer
Main Authors: Xin Xu, Siyue Wang, Julie A Tomolonis, Kshiti H Dholakia, Chunchao Zhang, Linjie Guo, Amy N Courtney, Julien Balzeau, Gabriel A Barragán, Gengwen Tian, Erica J Di Pierro, Leonid S Metelitsa
Format: Article
Language:English
Published: BMJ Publishing Group 2023-03-01
Online Access:https://jitc.bmj.com/content/11/3/e005478.full