USP18 enhances dengue virus replication by regulating mitochondrial DNA release

Abstract Dengue virus (DENV) infection remains a challenging health threat worldwide. Ubiquitin-specific protease 18 (USP18), which preserves the anti-interferon (IFN) effect, is an ideal target through which DENV mediates its own immune evasion. However, much of the function and mechanism of USP18...

Full description

Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Jenn-Haung Lai, De-Wei Wu, Chien-Hsiang Wu, Li-Feng Hung, Chuan-Yueh Huang, Shuk-Man Ka, Ann Chen, Ling-Jun Ho
Format:	Article
Language:	English
Published:	Nature Portfolio 2023-11-01
Online Access:	https://doi.org/10.1038/s41598-023-47584-w