Response to immune checkpoint blockade improved in pre-clinical model of breast cancer after bariatric surgery

Bariatric surgery is a sustainable weight loss approach, including vertical sleeve gastrectomy (VSG). Obesity exacerbates tumor growth, while diet-induced weight loss impairs progression. It remains unknown how bariatric surgery-induced weight loss impacts cancer progression or alters response to th...

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Bibliographic Details

Published in:	eLife
Main Authors:	Laura M Sipe, Mehdi Chaib, Emily B Korba, Heejoon Jo, Mary Camille Lovely, Brittany R Counts, Ubaid Tanveer, Jeremiah R Holt, Jared C Clements, Neena A John, Deidre Daria, Tony N Marion, Margaret S Bohm, Radhika Sekhri, Ajeeth K Pingili, Bin Teng, James A Carson, D Neil Hayes, Matthew J Davis, Katherine L Cook, Joseph F Pierre, Liza Makowski
Format:	Article
Language:	English
Published:	eLife Sciences Publications Ltd 2022-07-01
Subjects:	immunotherapy obesity sleeve gastrectomy breast cancer metabolic surgery PD-L1
Online Access:	https://elifesciences.org/articles/79143