Epigenetic signals associated with delirium replicated across four independent cohorts

Abstract Delirium is risky and indicates poor outcomes for patients. Therefore, it is crucial to create an effective delirium detection method. However, the epigenetic pathophysiology of delirium remains largely unknown. We aimed to discover reliable and replicable epigenetic (DNA methylation: DNAm)...

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Bibliographic Details

Published in:	Translational Psychiatry
Main Authors:	Yoshitaka Nishizawa, Kaitlyn C. Thompson, Takehiko Yamanashi, Nadia E. Wahba, Taku Saito, Pedro S. Marra, Takaaki Nagao, Tsuyoshi Nishiguchi, Kazuki Shibata, Kyosuke Yamanishi, Christopher G. Hughes, Pratik Pandharipande, Hyunkeun Cho, Matthew A. Howard, Hiroto Kawasaki, Hiroyuki Toda, Tetsufumi Kanazawa, Masaaki Iwata, Gen Shinozaki
Format:	Article
Language:	English
Published:	Nature Publishing Group 2024-07-01
Online Access:	https://doi.org/10.1038/s41398-024-02986-w