Genome-wide DNA methylation profiles analysis in primary warm autoimmune hemolytic anemia patients

ABSTRACTBackground Autoimmune hemolytic anemia (AIHA) is caused by auto-antibodies, secreted by overactivated B cells, directed against self-red blood cells, resulting in hemolysis. It found that aberrant DNA methylation in B cells can induce the production of autoantibodies. Therefore, we attempted...

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Bibliographic Details

Published in:	Hematology
Main Authors:	Manjun Zhao, Yang Zhang, Jin Yang, Lei Chen, Ziying Zhang, Huaquan Wang, Zonghong Shao, Limin Xing
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2023-12-01
Subjects:	Warm autoimmune hemolytic anemia B lymphocytes DNA methylation Methylation-specific PCR Bisulfite genomic sequence Autoimmunity disease
Online Access:	https://www.tandfonline.com/doi/10.1080/16078454.2023.2240138