Toxicity of L-asparaginase drugs in acute lymphoblastic leukemia treatment

Currently no therapy of acute lymphoblastic leukemia is conceivable without L-asparaginase drugs, with its antileukemic effect by extracellular asparagine depletion, thus preventing its admission to leukemic cell. Besides high antitumor effect, L-asparaginase drugs have side and toxic effects, such...

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Bibliographic Details
Published in:Онкогематология
Main Author: T. T. Valiev
Format: Article
Language:Russian
Published: ABV-press 2023-09-01
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Online Access:https://oncohematology.abvpress.ru/ongm/article/view/845