Osmotic Stress Interferes with DNA Damage Response and H2AX Phosphorylation in Human Keratinocytes

The human skin and in particular its outermost layer, the epidermis, protects the body from potentially harmful substances, radiation as well as excessive water loss. However, the interference between the various stress responses of the epidermal keratinocytes, which often occur simultaneously, is l...

Full description

Bibliographic Details

Published in:	Cells
Main Authors:	Laura Hoen, Christoph Rudisch, Michael Wick, Daniela Indenbirken, Adam Grundhoff, Florian Wegwitz, Stefan Kalkhof, Janosch Hildebrand
Format:	Article
Language:	English
Published:	MDPI AG 2022-03-01
Subjects:	keratinocytes UV radiation gene regulation DNA repair disorders osmotic stress
Online Access:	https://www.mdpi.com/2073-4409/11/6/959