Emerging Role of the KCNT1 Slack Channel in Intellectual Disability

The sodium-activated potassium KNa channels Slack and Slick are encoded by KCNT1 and KCNT2, respectively. These channels are found in neurons throughout the brain, and are responsible for a delayed outward current termed IKNa. These currents integrate into shaping neuronal excitability, as well as a...

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Bibliographic Details
Published in:Frontiers in Cellular Neuroscience
Main Authors: Grace E. Kim, Leonard K. Kaczmarek
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-07-01
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00209/full