Macrophage Coordination of the Interferon Lambda Immune Response

Lambda interferons (IFN-λs) are a major component of the innate immune defense to viruses, bacteria, and fungi. In human liver, IFN-λ not only drives antiviral responses, but also promotes inflammation and fibrosis in viral and non-viral diseases. Here we demonstrate that macrophages are primary res...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Scott A. Read, Ratna Wijaya, Mehdi Ramezani-Moghadam, Enoch Tay, Steve Schibeci, Christopher Liddle, Vincent W. T. Lam, Lawrence Yuen, Mark W. Douglas, David Booth, Jacob George, Golo Ahlenstiel
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2019-11-01
Subjects:	macrophage interferon lambda innate immunity liver Kupffer
Online Access:	https://www.frontiersin.org/article/10.3389/fimmu.2019.02674/full