Single‐extracellular vesicle (EV) analyses validate the use of L1 Cell Adhesion Molecule (L1CAM) as a reliable biomarker of neuron‐derived EVs

Abstract Isolation of neuron‐derived extracellular vesicles (NDEVs) with L1 Cell Adhesion Molecule (L1CAM)‐specific antibodies has been widely used to identify blood biomarkers of CNS disorders. However, full methodological validation requires demonstration of L1CAM in individual NDEVs and lower lev...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:Journal of Extracellular Vesicles
المؤلفون الرئيسيون: Carlos J Nogueras‐Ortiz, Erden Eren, Pamela Yao, Elizabeth Calzada, Christopher Dunn, Olga Volpert, Francheska Delgado‐Peraza, Maja Mustapic, Alexey Lyashkov, F Javier Rubio, Michael Vreones, Lesley Cheng, Yang You, Andrew F Hill, Tsuneya Ikezu, Erez Eitan, Edward J Goetzl, Dimitrios Kapogiannis
التنسيق: مقال
اللغة:الإنجليزية
منشور في: Wiley 2024-06-01
الموضوعات:
Alzheimer's disease
blood biomarkers
extracellular vesicles
L1CAM
neuron‐derived extracellular vesicles
الوصول للمادة أونلاين:https://doi.org/10.1002/jev2.12459

الانترنت

https://doi.org/10.1002/jev2.12459

مواد مشابهة