Investigating Single-Molecule Molecular Inversion Probes for Medium-Scale Targeted DNA Methylation Analysis

Background: Epigenetic biomarkers, particularly CpG methylation, are increasingly employed in clinical and forensic settings. However, we still lack a cost-effective, sensitive, medium-scale method for the analysis of hundreds to thousands of user-defined CpGs suitable for minute DNA input amounts (...

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Bibliographic Details
Published in:Epigenomes
Main Authors: Roy B. Simons, Hieab H. H. Adams, Manfred Kayser, Athina Vidaki
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Subjects:
age prediction
capture
DNA methylation
epigenetics
padlock probes
single-molecule molecular inversion probes
Online Access:https://www.mdpi.com/2075-4655/9/1/8

Internet

https://www.mdpi.com/2075-4655/9/1/8

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