Lineage-specific pathogenicity, immune evasion, and virological features of SARS-CoV-2 BA.2.86/JN.1 and EG.5.1/HK.3

Abstract SARS-CoV-2 JN.1 with an additional L455S mutation on spike when compared with its parental variant BA.2.86 has outcompeted all earlier variants to become the dominant circulating variant. Recent studies investigated the immune resistance of SARS-CoV-2 JN.1 but additional factors are specula...

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Bibliographic Details

Published in:	Nature Communications
Main Authors:	Yuanchen Liu, Xiaoyu Zhao, Jialu Shi, Yajie Wang, Huan Liu, Ye-Fan Hu, Bingjie Hu, Huiping Shuai, Terrence Tsz-Tai Yuen, Yue Chai, Feifei Liu, Hua-Rui Gong, Jiayan Li, Xun Wang, Shujun Jiang, Xiang Zhang, Yanliang Zhang, Xiangnan Li, Lei Wang, Madeline Hartnoll, Tianrenzheng Zhu, Yuxin Hou, Xiner Huang, Chaemin Yoon, Yang Wang, Yixin He, Minmin Zhou, Lianzhao Du, Xiaojuan Zhang, Wan-Mui Chan, Lin-Lei Chen, Jian-Piao Cai, Shuofeng Yuan, Jie Zhou, Jian-Dong Huang, Kwok-Yung Yuen, Kelvin Kai-Wang To, Jasper Fuk-Woo Chan, Bao-Zhong Zhang, Lei Sun, Pengfei Wang, Hin Chu
Format:	Article
Language:	English
Published:	Nature Portfolio 2024-10-01
Online Access:	https://doi.org/10.1038/s41467-024-53033-7