Calreticulin Translocation Aggravates Endoplasmic Reticulum Stress-associated Apoptosis during Cardiomyocyte Hypoxia/Reoxygenation

Background: Calreticulin (CRT) is major Ca 2+ -binding chaperone mainly resident in the endoplasmic reticulum (ER) lumen. Recently, it has been shown that non-ER CRT regulates a wide array of cellular responses. We previously found that CRT was up-regulated during hypoxia/reoxygenation (H/R) and thi...

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Bibliographic Details

Published in:	Chinese Medical Journal
Main Authors:	Fei-Fei Xu, Xiu-Hua Liu
Format:	Article
Language:	English
Published:	Wolters Kluwer 2015-01-01
Subjects:	Apoptosis; Calreticulin; CCAAT/Enhancer-binding Protein Homologous Protein; Endoplasmic Reticulum; Hypoxia/Reoxygenation
Online Access:	http://www.cmj.org/article.asp?issn=0366-6999;year=2015;volume=128;issue=3;spage=353;epage=360;aulast=Xu