Hypoxia Dictates Metabolic Rewiring of Tumors: Implications for Chemoresistance

Hypoxia is a condition commonly observed in the core of solid tumors. The hypoxia-inducible factors (HIF) act as hypoxia sensors that orchestrate a coordinated response increasing the pro-survival and pro-invasive phenotype of cancer cells, and determine a broad metabolic rewiring. These events favo...

詳細記述

書誌詳細

出版年:	Cells
主要な著者:	Dimas Carolina Belisario, Joanna Kopecka, Martina Pasino, Muhlis Akman, Enrico De Smaele, Massimo Donadelli, Chiara Riganti
フォーマット:	論文
言語:	英語
出版事項:	MDPI AG 2020-12-01
主題:	hypoxia cancer metabolic reprogramming chemoresistance
オンライン･アクセス:	https://www.mdpi.com/2073-4409/9/12/2598