Acute exposure to polystyrene nanoparticles promotes liver injury by inducing mitochondrial ROS-dependent necroptosis and augmenting macrophage-hepatocyte crosstalk

Abstract Background The global use of plastic materials has undergone rapid expansion, resulting in the substantial generation of degraded and synthetic microplastics and nanoplastics (MNPs), which have the potential to impose significant environmental burdens and cause harmful effects on living org...

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發表在:	Particle and Fibre Toxicology
Main Authors:	Junjie Fan, Li Liu, Yongling Lu, Qian Chen, Shijun Fan, Yongjun Yang, Yupeng Long, Xin Liu
格式:	Article
語言:	英语
出版:	BMC 2024-04-01
主題:	Polystyrene nanoparticles Liver injury RAW 264.7 cells Necroptosis Mitochondrial ROS Macrophage-hepatocyte crosstalk
在線閱讀:	https://doi.org/10.1186/s12989-024-00578-6