Understanding adaptation to fluconazole: comparative insights into tolerance and resistance in Saccharomyces cerevisiae and Candida albicans

IntroductionAntifungal resistance and tolerance are distinct responses exhibited by fungi when exposed to drugs. While considerable research has focused on azole tolerance in the human pathogen Candida albicans, studies in other fungal species remain limited.ObjectiveThis study aims to conduct a com...

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Bibliographic Details

Published in:	Frontiers in Cellular and Infection Microbiology
Main Authors:	Lijun Zheng, Yubo Dong, Jing Wang, Yonghui Jia, Weifang Wang, Yi Xu, Liangsheng Guo
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-05-01
Subjects:	fluconazole tolerance petite efflux ergosterol Saccharomyces cerevisiae
Online Access:	https://www.frontiersin.org/articles/10.3389/fcimb.2025.1519323/full