Sequence of androgen receptor-targeted vaccination with androgen deprivation therapy affects anti-prostate tumor efficacy

Rationale Androgen deprivation therapy (ADT) is the primary treatment for recurrent and metastatic prostate cancer. In addition to direct antitumor effects, ADT has immunomodulatory effects such as promoting T-cell infiltration and enhancing antigen processing/presentation. Previous studies in our l...

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Bibliographic Details
Published in:Journal for ImmunoTherapy of Cancer
Main Authors: Douglas G McNeel, Melissa Gamat-Huber, Anusha Muralidhar, Sita Vakkalanka
Format: Article
Language:English
Published: BMJ Publishing Group 2024-05-01
Online Access:https://jitc.bmj.com/content/12/5/e008848.full