The ELF3-TRIM22-MAVS signaling axis regulates type I interferon and antiviral responses

ABSTRACT Activation of the innate immune response is essential for host cells to restrict the dissemination of invading viruses and other pathogens. Proteins belonging to the tripartite motif (TRIM) family are key effectors in antiviral innate immunity. Among these, TRIM22, a RING-type E3 ubiquitin...

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Bibliographic Details
Published in:Journal of Virology
Main Authors: Qiaozhi Zhao, Pan Pan, Lirong Mo, Jiangtao Wu, Shengjie Liao, Hua Lu, Qiwei Zhang, Xiaoshen Zhang
Format: Article
Language:English
Published: American Society for Microbiology 2025-05-01
Subjects:
TRIM22
MAVS
NLRX1
innate immunity
IFN-β
antiviral response
Online Access:https://journals.asm.org/doi/10.1128/jvi.00004-25

Internet

https://journals.asm.org/doi/10.1128/jvi.00004-25

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