Combined transcriptomics and metabolomics to reveal the effects of copper exposure on the liver of rainbow trout(Oncorhynchus mykiss)

Copper (Cu) is recognized as an essential trace elements for the body; However, excessive levels of Cu can lead to toxic effects. We investigated the effects of Cu2+(75 μg/L, 150 μg/L, and 300 μg/L) on the rainbow trout liver. Combination of transcriptome and metabolome analyses, the regulatory mech...

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Bibliographic Details
Published in:Ecotoxicology and Environmental Safety
Main Authors: Junhao Lu, Jinqiang Quan, Jing Zhou, Zhe Liu, Jieping Ding, Tingting Shang, Guiyan Zhao, Lanlan Li, Yingcan Zhao, Xiangru Li, Jiajun Wu
Format: Article
Language:English
Published: Elsevier 2024-10-01
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Online Access:http://www.sciencedirect.com/science/article/pii/S0147651324010728