Germline variants profiling of BRCA1 and BRCA2 in Chinese Hakka breast and ovarian cancer patients

Abstract Objective To investigate the prevalence and spectrum of BRCA1 and BRCA2 mutations in Chinese Hakka patients with breast and ovarian cancer. Methods A total of 1,664 breast or ovarian cancer patients were enrolled for genetic testing at our hospital. Germline mutations of the BRCA gene were...

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Bibliographic Details
Published in:BMC Cancer
Main Authors: Yunuo Zhang, Heming Wu, Zhikang Yu, Liang Li, Jinhong Zhang, Xinhong Liang, Qingyan Huang
Format: Article
Language:English
Published: BMC 2022-08-01
Subjects:
BRCA gene
Breast cancer
Ovarian cancer
Variants
Hakka population
Online Access:https://doi.org/10.1186/s12885-022-09943-0

Internet

https://doi.org/10.1186/s12885-022-09943-0

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