A novel SLC8A1-ALK fusion in lung adenocarcinoma confers sensitivity to alectinib: A case report

ALK fusion genes are diverse. Approximately 30 different ALK fusion protein partners have been described previously, and some of these fusion proteins have been reported to be effective against ALK-tyrosine kinase inhibitor (TKI). ALK rearrangements often occur at a common breakpoint in exon 20 of t...

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Bibliographic Details

Published in:	Open Life Sciences
Main Authors:	Deng Ling, Tian Panwen, Qiu Zhixin, Wang Ke, Li Yalun
Format:	Article
Language:	English
Published:	De Gruyter 2022-08-01
Subjects:	lung adenocarcinoma slc8a1-alk alk fusion protein partners alectinib
Online Access:	https://doi.org/10.1515/biol-2022-0090