Validating reference-based algorithms to determine cell-type heterogeneity in ovarian cancer DNA methylation studies
Abstract Information about cell composition in tissue samples is crucial for biomarker discovery and prognosis. Specifically, cancer tissue samples present challenges in deconvolution studies due to mutations and genetic rearrangements. Here, we optimized a robust, DNA methylation-based protocol, to...
| 发表在: | Scientific Reports |
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| Main Authors: | , , , |
| 格式: | 文件 |
| 语言: | 英语 |
| 出版: |
Nature Portfolio
2024-05-01
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| 主题: | |
| 在线阅读: | https://doi.org/10.1038/s41598-024-61857-y |