Super‐Resolution Infrared Imaging of Polymorphic Amyloid Aggregates Directly in Neurons

Abstract Loss of memory during Alzheimer's disease (AD), a fatal neurodegenerative disorder, is associated with neuronal loss and the aggregation of amyloid proteins into neurotoxic β‐sheet enriched structures. However, the mechanism of amyloid protein aggregation is still not well understood d...

Full description

Bibliographic Details

Published in:	Advanced Science
Main Authors:	Oxana Klementieva, Christophe Sandt, Isak Martinsson, Mustafa Kansiz, Gunnar K. Gouras, Ferenc Borondics
Format:	Article
Language:	English
Published:	Wiley 2020-03-01
Subjects:	Alzheimer's disease disease mechanism optical photothermal infrared spectroscopy protein aggregation structure–function relation super‐resolution
Online Access:	https://doi.org/10.1002/advs.201903004