Identification of pyroptosis related genes and subtypes in atherosclerosis using multiomic and single cell analysis

Abstract Atherosclerosis (AS), the leading cause of cardiovascular diseases, is a chronic inflammatory disorder involving lipid metabolism, immune dysregulation, and cell death. Pyroptosis, a form of inflammatory programmed cell death, is implicated in AS progression, yet its molecular mechanisms an...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Kaisheng Jiang, Yang He, Bingjie Hu, Li Quan, Longyun Peng, Juntao Tian, Nan Zhou, Erwen Huang, Qianhao Zhao
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-07-01
Subjects:	Atherosclerosis Pyroptosis TREM2 Multi-omics analysis Immune microenvironment
Online Access:	https://doi.org/10.1038/s41598-025-04398-2