ROLE OF GENETIC VARIABILITY IN METABOLIC PATHWAYS ON CISPLATIN-INDUCED KIDNEY INJURY IN HEAD AND NECK CANCER PATIENTS

Introduction/Justification: Head and neck squamous cell carcinoma (HNSCC) is a prevalent malignancy responsible for approximately 5.0% of global cancer deaths. The standard treatment for locally advanced HNSCC involves cisplatin (CDDP)-based chemotherapy and radiotherapy, which can lead to significa...

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Bibliographic Details

Published in:	Hematology, Transfusion and Cell Therapy
Main Authors:	Ericka Francislaine Dias Costa, Ana Maria Castro Ferreira, Marilda Mazzali, Gustavo Jacob Lourenço, Carmen Silvia Passos Lima
Format:	Article
Language:	English
Published:	Elsevier 2025-05-01
Subjects:	Cisplatin Head and neck squamous cell carcinoma Nephrotoxicity Single nucleotide variants
Online Access:	http://www.sciencedirect.com/science/article/pii/S2531137925000355