Calcium Handling Machinery and Sarcomere Assembly are Impaired Through Multipronged Mechanisms in Cancer Cytokine‐Induced Cachexia

Abstract Background Cachexia is a severe form of muscle wasting disorder particularly observed in patients with advanced cancer. The absence of effective strategies to ameliorate cachexia indicates our poor understanding of the mechanisms of cachexia. By employing system‐wide approaches, we investig...

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التفاصيل البيبلوغرافية

الحاوية / القاعدة:	Journal of Cachexia, Sarcopenia and Muscle
المؤلفون الرئيسيون:	Luis Vincens Gand, Chiara Lanzuolo, Mugeng Li, Valentina Rosti, Natalie Weber, Dongchao Lu, Christian Bär, Thomas Thum, Andreas Pich, Theresia Kraft, Mamta Amrute‐Nayak, Arnab Nayak
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	Wiley 2025-04-01
الموضوعات:	calcium homeostasis cancer secreted pro‐inflammatory cytokine‐induced cachexia chromatin organization proteostasis RNA polymerase II sarcoplasmic reticulum
الوصول للمادة أونلاين:	https://doi.org/10.1002/jcsm.13776