Concurrent BCR‐ABL1 and core binding factor beta rearrangement in de novo acute myeloid leukemia: A case report and review of literature

Abstract A distinct subset of acute myeloid leukemia (AML) is characterized by the presence of the Philadelphia chromosome (Ph+), due to reciprocal translocation t(9;22)(q34;q11.2). This chromosomal rearrangement leads to the fusion of the breakpoint cluster region (BCR) gene on chromosome 22 with t...

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Bibliographic Details
Published in:eJHaem
Main Authors: Brittany Salter, Sarah Ge, Amy Tam, Suzanne Demczuk, Darci Butcher, Elizabeth McCready, Dina Khalaf
Format: Article
Language:English
Published: Wiley 2024-06-01
Subjects:
Online Access:https://doi.org/10.1002/jha2.895