Genome-Wide Association Study of Tacrolimus Pharmacokinetics Identifies Novel Single Nucleotide Polymorphisms in the Convalescence and Stabilization Periods of Post-transplant Liver Function

After liver transplantation, the liver function of a patient is gradually restored over a period of time that can be divided into a convalescence period (CP) and a stabilizing period (SP). The plasma concentration of tacrolimus, an immunosuppressant commonly used to prevent organ rejection, varies a...

Full description

Bibliographic Details

Published in:	Frontiers in Genetics
Main Authors:	Yuan Liu, Chengdong Zhang, Lei Li, Baochi Ou, Liyun Yuan, Tao Zhang, Junwei Fan, Zhihai Peng
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2019-05-01
Subjects:	GWAS CYP3A5 exome tacrolimus FAM26F
Online Access:	https://www.frontiersin.org/article/10.3389/fgene.2019.00528/full