Interplay between proteostasis pathways and innate immune responses in Caenorhabditis elegans

ABSTRACT Microbial pathogens frequently manipulate host protein homeostasis to undermine immunity by targeting protein synthesis, folding, trafficking, and degradation. Conversely, effective immune responses themselves impose substantial proteostatic demands, as the rapid production of antimicrobial...

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Bibliographic Details

Published in:	Infection and Immunity
Main Authors:	Annesha Ghosh, Jogender Singh
Format:	Article
Language:	English
Published:	American Society for Microbiology 2026-05-01
Subjects:	C. elegans endoplasmic reticulum mitochondria proteasome unfolded protein response
Online Access:	https://journals.asm.org/doi/10.1128/iai.00037-26