Rare Dysfunctional Complement Factor I Genetic Variants and Progression to Advanced Age-Related Macular Degeneration

Purpose: To evaluate associations between rare dysfunctional complement factor I (CFI) genetic variant status and progression to advanced age-related macular degeneration (AAMD), geographic atrophy (GA), and neovascular disease (NV). Design: Prospective, longitudinal study Participants: Patients age...

Full description

Bibliographic Details

Published in:	Ophthalmology Science
Main Authors:	Johanna M. Seddon, MD, Bernard Rosner, PhD, Dikha De, MPH, Tianxiao Huan, PhD, Anuja Java, MD, John Atkinson, MD
Format:	Article
Language:	English
Published:	Elsevier 2023-06-01
Subjects:	Advanced age-related macular degeneration Complement factor I Genetic variants Geographic atrophy Neovascular disease
Online Access:	http://www.sciencedirect.com/science/article/pii/S2666914522001543