The autophagy–lysosome pathway: a potential target in the chemical and gene therapeutic strategies for Parkinson’s disease

Parkinson’s disease is a common neurodegenerative disease with movement disorders associated with the intracytoplasmic deposition of aggregate proteins such as α-synuclein in neurons. As one of the major intracellular degradation pathways, the autophagy-lysosome pathway plays an important role in el...

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Bibliographic Details

Published in:	Neural Regeneration Research
Main Authors:	Fengjuan Jiao, Lingyan Meng, Kang Du, Xuezhi Li
Format:	Article
Language:	English
Published:	Wolters Kluwer Medknow Publications 2025-01-01
Subjects:	autophagy chemical therapy gene therapy parkinson’s disease α-synuclein
Online Access:	https://journals.lww.com/10.4103/NRR.NRR-D-23-01195