Induction of Apoptosis and Cytotoxicity by Raphasatin in Human Breast Adenocarcinoma MCF-7 Cells

Glucoraphasatin (GRH), a glucosinolate present abundantly in the plants of the <i>Brassicaceae</i> family, is hydrolyzed by myrosinase to raphasatin, which is considered responsible for its cancer chemopreventive activity; however, the underlying mechanisms of action have not been invest...

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Bibliographic Details

Published in:	Molecules
Main Authors:	Muhammad Din Ibrahim, Saie Brindha Kntayya, Nooraini Mohd Ain, Renato Iori, Costas Ioannides, Ahmad Faizal Abdull Razis
Format:	Article
Language:	English
Published:	MDPI AG 2018-11-01
Subjects:	glucoraphasatin raphasatin glucosinolates isothiocyanates human breast adenocarcinoma cell line cytotoxicity apoptosis cell cycle
Online Access:	https://www.mdpi.com/1420-3049/23/12/3092