NUP98::NSD1 and FLT3/ITD co-expression is an independent predictor of poor prognosis in pediatric AML patients

Abstract Objective Patients who carry NUP98::NSD1 or FLT3/ITD mutations are reported to have poor prognosis. Previous studies have confidently reported that the poor outcome in younger AML patients is owning to dual NUP98::NSD1 and FLT3/ITD positivity, with a high overlap for those two genetic lesio...

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Bibliographic Details

Published in:	BMC Pediatrics
Main Authors:	Jing-wen Wang, Yu-Li, Xing-Ge Yang, Lu-Hong Xu
Format:	Article
Language:	English
Published:	BMC 2024-08-01
Subjects:	NUP98::NSD1 Nucleoporin gene 98 FLT3/ITD Pediatric Acute myeloid leukemia (AML)
Online Access:	https://doi.org/10.1186/s12887-024-05007-3