Phylogenomic, structural, and cell biological analyses reveal that Stenotrophomonas maltophilia replicates in acidified Rab7A-positive vacuoles of Acanthamoeba castellanii

ABSTRACTAcanthamoeba species are clinically relevant free-living amoebae (FLA) ubiquitously found in soil and water bodies. Metabolically active trophozoites graze on diverse microbes via phagocytosis. However, functional studies on Rab GTPases (Rabs), which are critical for controlling vesicle traf...

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Bibliographic Details

Published in:	Microbiology Spectrum
Main Authors:	Javier Rivera, Julio C. Valerdi-Negreros, Diana M. Vázquez-Enciso, Fulvia-Stefany Argueta-Zepeda, Pablo Vinuesa
Format:	Article
Language:	English
Published:	American Society for Microbiology 2024-03-01
Subjects:	Acanthamoeba expression plasmids small Rab GTPases endocytic pathway phagocytosis vacuole acidification
Online Access:	https://journals.asm.org/doi/10.1128/spectrum.02988-23