Tumour response to hypoxia: understanding the hypoxic tumour microenvironment to improve treatment outcome in solid tumours

Hypoxia is a common feature of solid tumours affecting their biology and response to therapy. One of the main transcription factors activated by hypoxia is hypoxia-inducible factor (HIF), which regulates the expression of genes involved in various aspects of tumourigenesis including proliferative ca...

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Bibliographic Details

Published in:	Frontiers in Oncology
Main Authors:	Kamilla JA. Bigos, Conrado G. Quiles, Sapna Lunj, Danielle J. Smith, Mechthild Krause, Esther GC. Troost, Catharine M. West, Peter Hoskin, Ananya Choudhury
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-01-01
Subjects:	hypoxia tumour microenvironment extracellular matrix immune cells cancer associated fibroblasts
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2024.1331355/full