Bone Marrow-Derived CD44+ Cells Migrate to Tissue-Engineered Constructs via SDF-1/CXCR4-JNK Pathway and Aid Bone Repair

Background and Aims. Host-derived cells play crucial roles in the regeneration process of tissue-engineered constructs (TECs) during the treatment of large segmental bone defects (LSBDs). However, their identity, source, and cell recruitment mechanisms remain elusive. Methods. A complex model was cr...

詳細記述

書誌詳細
出版年:Stem Cells International
主要な著者: Yanzhu Lu, Junchao Xing, Xiaolong Yin, Xiaobo Zhu, Aijun Yang, Jiyue Luo, Jing Gou, Shiwu Dong, Jianzhong Xu, Tianyong Hou
フォーマット: 論文
言語:英語
出版事項: Wiley 2019-01-01
オンライン・アクセス:http://dx.doi.org/10.1155/2019/1513526