Locus coeruleus activity while awake is associated with REM sleep quality in older individuals

BACKGROUND The locus coeruleus (LC) is the primary source of norepinephrine in the brain and regulates arousal and sleep. Animal research shows that it plays important roles in the transition between sleep and wakefulness, and between slow wave sleep and rapid eye movement sleep (REMS). It is unclea...

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Bibliographic Details

Published in:	JCI Insight
Main Authors:	Ekaterina Koshmanova, Alexandre Berger, Elise Beckers, Islay Campbell, Nasrin Mortazavi, Roya Sharifpour, Ilenia Paparella, Fermin Balda, Christian Berthomier, Christian Degueldre, Eric Salmon, Laurent Lamalle, Christine Bastin, Maxime Van Egroo, Christophe Phillips, Pierre Maquet, Fabienne Collette, Vincenzo Muto, Daphne Chylinski, Heidi I.L. Jacobs, Puneet Talwar, Siya Sherif, Gilles Vandewalle
Format:	Article
Language:	English
Published:	American Society for Clinical investigation 2023-10-01
Subjects:	Aging Neuroscience
Online Access:	https://doi.org/10.1172/jci.insight.172008