Unraveling gut microbiome alterations and metabolic signatures in hereditary transthyretin amyloidosis

ABSTRACT Hereditary transthyretin amyloidosis (hATTR) is a rare, often fatal disease characterized by the abnormal aggregation of atypical transthyretin fibrils. Given the variability in the penetrance and clinical manifestations of hATTR, the role of nongenetic factors, particularly those related t...

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Bibliographic Details

Published in:	Microbiology Spectrum
Main Authors:	Hanyu Li, Zeyuan Wang, Shan He, Xinyue Zhao, Qingyang Wu, Yueshen Sun, Yue Fan, Xiaomin Hu, Zhuang Tian, Shuyang Zhang
Format:	Article
Language:	English
Published:	American Society for Microbiology 2025-07-01
Subjects:	hereditary transthyretin amyloidosis hATTR cardiac amyloidosis metabolome metagenomics microbiome
Online Access:	https://journals.asm.org/doi/10.1128/spectrum.02302-24