Sequence to Medical Phenotypes: A Framework for Interpretation of Human Whole Genome DNA Sequence Data.

High throughput sequencing has facilitated a precipitous drop in the cost of genomic sequencing, prompting predictions of a revolution in medicine via genetic personalization of diagnostic and therapeutic strategies. There are significant barriers to realizing this goal that are related to the diffi...

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Bibliographic Details

Published in:	PLoS Genetics
Main Authors:	Frederick E Dewey, Megan E Grove, James R Priest, Daryl Waggott, Prag Batra, Clint L Miller, Matthew Wheeler, Amin Zia, Cuiping Pan, Konrad J Karzcewski, Christina Miyake, Michelle Whirl-Carrillo, Teri E Klein, Somalee Datta, Russ B Altman, Michael Snyder, Thomas Quertermous, Euan A Ashley
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2015-10-01
Online Access:	https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1005496&type=printable