Identification of potent inhibitors of Leishmania donovani and Leishmania infantum chagasi, the causative agents of Old and New World visceral leishmaniasis

Abstract The drug discovery pipeline for neglected kinetoplastid diseases remains sparse. In particular, the field of leishmaniasis drug discovery has had limited success in translating potential drug candidates into viable therapies. Here, we describe the development of two lead compounds, BZ-1 and...

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發表在:	Communications Biology
Main Authors:	Bilal Zulfiqar, Fabio Antonio Colombo, Juliana Barbosa Nunes, Patricia Ferreira Espuri, Aurea Favero Ferreira, Sujatha Manthri, Manu De Rycker, Marcos Jose Marques, Vicky M. Avery
格式:	Article
語言:	英语
出版:	Nature Portfolio 2025-07-01
在線閱讀:	https://doi.org/10.1038/s42003-025-08386-0